FEATURES

FAMILY

DESCRIPTION

Also known as PILB_THET8, pilB. ATPase component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a form of surface-associated motility facilitated by cycles of extension, adhesion, and retraction of T4P fibers (By similarity) (PubMed:29717025). Acts as a molecular motor to provide the energy that is required for biogenesis of the pilus and the extrusion of substrates generated in the cytoplasm (PubMed:27667690). PilB ATPase activity is also essential for T4P extension while antagonist PilT ATPase activity is required for T4P retraction (By similarity). Homohexamer (PubMed:29717025, PubMed:27667690). Interacts with PilC (By similarity).

Also known as PILB_THET8, pilB. ATPase component of the type IV pilus (T4P) that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching, a for ...

EXTERNAL LINKS

pilB

Mutations

Mutation(s) distribution

Mutations table