FEATURES

FAMILY

cation transport ATPase (P-type) (TC 3.A.3) family

DESCRIPTION

Also known as AT2A3_MOUSE, Atp2a3. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Interacts with sarcolipin (SLN) (By similarity). Interacts with phospholamban (PLN) (By similarity). Interacts with myoregulin (MRLN). Interacts with DWORF (By similarity). Interacts VMP1 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

Atp2a3

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

Atp2a3

Molecular Synopsis