FEATURES

FAMILY

DESCRIPTION

Also known as MDAR3_ORYSJ, MDAR3, MDHAR3. Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process. Ascorbate is a major antioxidant against reactive oxygen species (ROS) and nitric oxide (NO) (PubMed:24376554, PubMed:27652777). Can use NADPH as electron donor, but possesses lower activity compared to NADH as electron donor (PubMed:27652777).

EXTERNAL LINKS

uniprot
enzyme classification

MDAR3

Monodehydroascorbate reductase 3, cytosolic

Mutations

Mutation(s) distribution

Mutations table

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