FEATURES

DESCRIPTION

Also known as ANKS6_HUMAN, ANKS6, ANKRD14, PKDR1, SAMD6. Required for renal function. Homooligomer (By similarity). Central component of a complex containing at least ANKS6, INVS, NEK8 and NPHP3 (PubMed:23793029). ANKS6 may organize complex assembly by linking INVS and NPHP3 to NEK8 and INVS may target the complex to the proximal ciliary axoneme (PubMed:23793029). Interacts (via SAM domain) with BICC1 (via KH domains) in an RNA-dependent manner (By similarity). Interacts (via SAM domain) with ANKS3 (via SAM domain) (PubMed:24998259).

Also known as ANKS6_HUMAN, ANKS6, ANKRD14, PKDR1, SAMD6. Required for renal function. Homooligomer (By similarity). Central component of a complex containing at least ANKS6, INVS, NEK8 and NPHP3 ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ANKS6

Mutations

Mutation(s) distribution

Mutations table