FEATURES

FAMILY

DESCRIPTION

Also known as ATG14_KLULA, ATG14. Required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I. This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure. ATG14 mediates the specific binding of the VPS34 PI3-kinase complex I to the preautophagosomal structure (PAS) (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

ATG14

Autophagy-related protein 14

ATG14

Molecular Synopsis