FEATURES

FAMILY

DESCRIPTION

Also known as UPPS_PECAS, uppS. Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E, 6E)-farnesyl diphosphate (E, E-FPP) to yield (2Z, 6Z, 10Z, 14Z, 18Z, 22Z, 26Z, 30Z, 34E, 38E)-undecaprenyl diphosphate (di-trans, octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

uppS

Ditrans, polycis-undecaprenyl-diphosphate synthase ((2E, 6E)-farnesyl-diphosphate specific)

uppS

Structural Ligandability

Domains Chains

Distribution