FEATURES

FAMILY

DESCRIPTION

Also known as RCE1_METMP, rce1. Endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine, A is an aliphatic amino acid and X is any amino acid. Cleaves the CAAX motif C-terminal to both P1 and P1' positions. Hydrolysis depends on a farnesylated cysteine residue and no activity is shown towards geranylgeranylated peptides.

EXTERNAL LINKS

uniprot
enzyme classification

rce1

CAAX prenyl protease 2

rce1

Molecular Synopsis