FEATURES

FAMILY

DESCRIPTION

Also known as CAR_NOCIO, car. Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes. Catalyzes the reduction of a very wide range of aliphatic carboxylic acids as well as many aryl carboxylic acids. Aryl carboxylic acid substrates include substituted benzoic acids, phenyl-substituted aliphatic acids, heterocyclic carboxylic acids, and polyaromatic ring carboxylic acids. Cannot reduce benzaldehyde to benzyl alcohol. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

car

Mutations

Mutation(s) distribution

Mutations table