FEATURES

FAMILY

DESCRIPTION

Also known as DCP1_ASHGO, DCP1. Component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Decapping is the major pathway of mRNA degradation in yeast. It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body (By similarity). Component of the decapping complex.

EXTERNAL LINKS

uniprot
enzyme classification

DCP1

mRNA-decapping enzyme subunit 1

DCP1

Structural Ligandability

Domains Chains

Distribution