FEATURES

FAMILY

DESCRIPTION

Also known as AMGO2_HUMAN, AMIGO2, ALI1. Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. Binds itself as well as AMIGO1 and AMIGO3.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

AMIGO2

Amphoterin-induced protein 2

ligandability Mutations

AMIGO2

Molecular Synopsis