FEATURES

DESCRIPTION

Also known as TAXB1_HUMAN, TAX1BP1, T6BP. Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. Homooligomer. Interacts with TRAF6 in a IL-1-dependent manner. Interacts with TNFAIP3. Interacts with STARD13. Interacts with the HTLV-1 protein Tax-1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TAX1BP1

Tax1-binding protein 1

TAX1BP1

Molecular Synopsis