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FEATURES

DESCRIPTION

Also known as VOPS_VIBPA, vopS. Adenylyltransferase involved in virulence by mediating the addition of adenosine 5'-monophosphate (AMP) to specific threonine residue of host Rho GTPases RhoA, Rac and Cdc42. The resulting AMPylation prevents the interaction of Rho GTPases with downstream effectors, thereby inhibiting actin assembly in infected cells.

Also known as VOPS_VIBPA, vopS. Adenylyltransferase involved in virulence by mediating the addition of adenosine 5'-monophosphate (AMP) to specific threonine residue of host Rho GTPases RhoA, Rac an ...

EXTERNAL LINKS

uniprot
enzyme classification

vopS

Protein adenylyltransferase VopS

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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