FEATURES

FAMILY

DESCRIPTION

Also known as ST2A8_MOUSE, Sult2a8, 2810007J24Rik. Hepatic sulfotransferase involved in the maintenance of bile acid homeostasis and energy balance. Catalyzes the transfer of sulfonate group from 3'-phosphoadenylyl sulfate (PAPS) to the 7-alpha hydroxy group of primary bile acids to form 7-monosulfate derivatives in the pathway of bile acid elimination. Displays high catalytic efficiency toward cholate, chenodeoxycholate and their glycine and taurine conjugates.

EXTERNAL LINKS

uniprot
enzyme classification

Sult2a8

Mutations

Mutation(s) distribution

Mutations table