FEATURES

FAMILY

DESCRIPTION

Also known as AL4A1_MOUSE, Aldh4a1. Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

Aldh4a1

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

Aldh4a1

Molecular Synopsis