FEATURES

FAMILY

DESCRIPTION

Also known as ESCO2_MOUSE, Esco2. Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3.

EXTERNAL LINKS

uniprot
enzyme classification

Esco2

N-acetyltransferase ESCO2

Mutations

Mutation(s) distribution

Mutations table

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