FEATURES

FAMILY

DESCRIPTION

Also known as SPNS2_HUMAN, SPNS2. Acts a a crucial lysosphingolipid sphingosine 1-phosphate (S1P) transporter involved in S1P secretion and function (PubMed:19074308, PubMed:23180825). S1P is a bioactive signaling molecule that regulates many physiological processes important for the development and for the immune system. Regulates levels of S1P and the S1P gradient that exists between the high circulating concentrations of S1P and low tissue levels that control lymphocyte trafficking (PubMed:19074308, PubMed:23180825).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SPNS2

Protein spinster homolog 2

SPNS2

Molecular Synopsis