FEATURES

FAMILY

DESCRIPTION

Also known as ETKMT_HUMAN, ETFBKMT, C12orf72, METTL20. Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria (PubMed:25023281, PubMed:25416781). Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain (PubMed:25416781). Interacts with HSPD1; this protein may possibly be a methylation substrate.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ETFBKMT

Electron transfer flavoprotein beta subunit lysine methyltransferase

Structural Ligandability

Domains Chains

0 chains assessed

1 chain not associated with a domain

ETFBKMT

Structural Ligandability

Domains Chains

Distribution