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FEATURES

FAMILY

HMG-CoA synthase family

DESCRIPTION

Also known as HMCS1_MOUSE, Hmgcs1. Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis. Homodimer.

Also known as HMCS1_MOUSE, Hmgcs1. Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for ch ...

EXTERNAL LINKS

uniprot
enzyme classification

Hmgcs1

Hydroxymethylglutaryl-CoA synthase, cytoplasmic

Structural Ligandability

Domains Chains

Distribution

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