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FEATURES

FAMILY

DESCRIPTION

Also known as IMDH_CHLTE, guaB. Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Homotetramer.

Also known as IMDH_CHLTE, guaB. Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanin ...

EXTERNAL LINKS

uniprot
enzyme classification

guaB

Inosine-5'-monophosphate dehydrogenase

Molecular Synopsis

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