FEATURES

FAMILY

DESCRIPTION

Also known as RQL4A_ARATH, RECQL4A, RECQ4A, RQL4A, SGS1. 3'-5' DNA helicase involved in DNA repair (PubMed:16146519, PubMed:18000056, PubMed:19096507). Required for the maintenance of genome stability by modulation of the DNA damage response and repression of crossovers. Confers resistance to genotoxic stress (PubMed:16146519, PubMed:18000056). Suppresses spontaneous homologous recombination (HR) events in somatic cells together with its partners RMI1 and TOP3A (PubMed:19096507). Contributes to the maintenance of chromosome integrity during meiosis. Involved in the removal of telomeric bridges that appear to arise during meiotic recombination. Required to resolve or dissolve MSH4-dependent telomeric associations. Does not seem required for chiasma formation (PubMed:21265901).

Also known as RQL4A_ARATH, RECQL4A, RECQ4A, RQL4A, SGS1. 3'-5' DNA helicase involved in DNA repair (PubMed:16146519, PubMed:18000056, PubMed:19096507). Required for the maintenance of genome sta ...

RECQL4A

Structural Ligandability

Domains Chains

Distribution