FEATURES

FAMILY

NADH:flavin oxidoreductase/NADH oxidase family

DESCRIPTION

Also known as OPR1_ARATH, OPR1. Specifically cleaves olefinic bonds in alpha, beta-unsaturated carbonyls and may be involved in detoxification or modification of these reactive compounds (PubMed:9346960, PubMed:10872231). May be involved in the biosynthesis or metabolism of oxylipin signaling molecules (Probable). In vitro, reduces 9R, 13R-12-oxophytodienoic acid (9R, 13R-OPDA) to 9R, 13R-OPC-8:0, but only poorly 9S, 13S-OPDA, the natural precursor of jasmonic acid (PubMed:10872231). Can detoxify the explosive 2, 4, 6-trinitrotoluene (TNT) in vitro and in vivo by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT) (PubMed:19605548).

EXTERNAL LINKS

OPR1

12-oxophytodienoate reductase 1

OPR1

Molecular Synopsis