FEATURES

FAMILY

DESCRIPTION

Also known as D106A_HUMAN, DEFB106A, DEFB106B, BD6, DEFB106, DEFB6. Has antibacterial activity (PubMed:12600824). Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:23938203). Monomer (PubMed:23938203). Interacts with CCR2 (via extracellular N-terminal region); this interaction may preferentially require specific tyrosine sulfation on CCR2 (PubMed:23938203).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DEFB106A, DEFB106B

Beta-defensin 106

DEFB106A, DEFB106B

Molecular Synopsis