FEATURES

FAMILY

DESCRIPTION

Also known as TMTC2_HUMAN, TMTC2. Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TMTC2

Protein O-mannosyl-transferase TMTC2

TMTC2

Molecular Synopsis