FEATURES

FAMILY

class-I pyridoxal-phosphate-dependent aminotransferase family

DESCRIPTION

Also known as AADAT_HUMAN, AADAT, KAT2, KYAT2. Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). Homodimer.

Also known as AADAT_HUMAN, AADAT, KAT2, KYAT2. Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

AADAT

Mutations

Mutation(s) distribution

Mutations table