FEATURES

FAMILY

DESCRIPTION

Also known as NAT8L_HUMAN, NAT8L, CML3. Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NAT8L

N-acetylaspartate synthetase

NAT8L

Molecular Synopsis