FEATURES

DESCRIPTION

Also known as LEMD2_HUMAN, LEMD2. Involved in nuclear structure organization (PubMed:16339967). Required for maintaining the integrity of the nuclear envelope (PubMed:17097643)., Required for embryonic development and is involved in regulation of several signaling pathways such as MAPK and AKT. Required for myoblast differentiation involving regulation of ERK signaling (By similarity). Binds to the lamin tail, in vitro.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

LEMD2

LEM domain-containing protein 2

LEMD2

Molecular Synopsis