FEATURES

FAMILY

Monocarboxylate porter (TC 2.A.1.13) family

DESCRIPTION

Also known as MOT11_HUMAN, SLC16A11, MCT11. Proton-linked monocarboxylate transporter. It catalyzes the transport of pyruvate across the plasma membrane (PubMed:28666119). Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids (PubMed:24390345). Interacts with isoform 2 of BSG.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC16A11

Monocarboxylate transporter 11

SLC16A11

Molecular Synopsis