FEATURES

DESCRIPTION

Also known as MDGA1_HUMAN, MDGA1, MAMDC3. Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2. Interacts heterophilically through its MAM domain with proteins in axon-rich regions and through its Ig-like domains with proteins in differentiating muscle (By similarity). Interacts (through the Ig-like domains) with NLGN2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MDGA1

MAM domain-containing glycosylphosphatidylinositol anchor protein 1

MDGA1

Molecular Synopsis