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Also known as FCG2A_PANTR, FCGR2A. Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens (By similarity). Interacts with INPP5D/SHIP1 and INPPL1/SHIP2, regulating its function. Interacts with APCS and FGR. Interacts with HCK (By similarity).

Also known as FCG2A_PANTR, FCGR2A. Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Pr ...

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uniprot
enzyme classification

FCGR2A

Low affinity immunoglobulin gamma Fc region receptor II-a

Structural Ligandability

Domains Chains

Distribution

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