FEATURES

FAMILY

Organic cation transporter (TC 2.A.1.19) family

DESCRIPTION

Also known as S22A8_HUMAN, SLC22A8, OAT3. Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2, 4-dichloro-phenoxyacetate (2, 4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC22A8

Solute carrier family 22 member 8

SLC22A8

Molecular Synopsis