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FEATURES

FAMILY

Isocitrate lyase family

DESCRIPTION

Also known as ACEA2_MYCTO, icl2, aceA-2. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.

Also known as ACEA2_MYCTO, icl2, aceA-2. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of t ...

EXTERNAL LINKS

uniprot
enzyme classification

icl2

Isocitrate lyase 2

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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