FEATURES

FAMILY

krueppel C2H2-type zinc-finger protein family

DESCRIPTION

Also known as ZN473_HUMAN, ZNF473, KIAA1141, ZFP100. Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. Interacts with the SLBP/pre-mRNA complex but not with SLBP alone. Interacts with LSM11 in a U7 snRNP-dependent manner.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ZNF473

Zinc finger protein 473

ZNF473

Molecular Synopsis