FEATURES

FAMILY

DESCRIPTION

Also known as T170A_HUMAN, TMEM170A, TMEM170. Acts as a regulator of endoplasmic reticulum (ER) and nuclear envelope (NE) morphogenesis. Affects the ratio between tubular ER and ER sheets by promoting sheet formation at the expense of tubules. Influences NE expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins (PubMed:26906412). Interacts with RTN4 (PubMed:26906412).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TMEM170A

Transmembrane protein 170A

TMEM170A

Molecular Synopsis