FEATURES

FAMILY

DESCRIPTION

Also known as CHDC_LISMO, chdC, hemQ. Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:27758026, PubMed:31423350). Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway (PubMed:27758026, PubMed:31423350, PubMed:29536725). The reaction occurs in a stepwise manner with a three-propionate intermediate (PubMed:27758026, PubMed:31423350). Homopentamer (PubMed:25602700, PubMed:27758026, PubMed:31423350). Homohexamer in solution (PubMed:25602700).

EXTERNAL LINKS

uniprot
enzyme classification

chdC

Mutations

Mutation(s) distribution

Mutations table