FEATURES

FAMILY

mandelate racemase/muconate lactonizing enzyme family

DESCRIPTION

Also known as TAGAD_SALTY, STM3697. Catalyzes the efficient dehydration of both L-talarate (also called L-altrarate) and galactarate to 5-keto-4-deoxy-D-glucarate (5-KDG) (PubMed:17649980, PubMed:29248502). Also catalyzes the epimerization of L-talarate to galactarate; epimerization occurs in competition with dehydration. Is required for the utilization of L-talarate as a carbon source. Also functions in galactarate utilization. Is not active on other acid sugars (PubMed:17649980). Homooctamer; tetramer of dimers.

EXTERNAL LINKS

uniprot
enzyme classification

STM3697

L-talarate/galactarate dehydratase

STM3697

Molecular Synopsis