FEATURES

FAMILY

DESCRIPTION

Also known as NAGZ_SALTY, nagZ. Plays a role in peptidoglycan recycling by cleaving the terminal beta-1, 4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Plays a role in beta-lactam antibiotic resistance via its role in generating anhydro-N-acetylmuramic acid-linked peptides; these peptides function as signaling molecules that induce high-level expression of the beta-lactamase AmpC.

EXTERNAL LINKS

uniprot
enzyme classification

nagZ

Beta-hexosaminidase

nagZ

Molecular Synopsis