FEATURES

FAMILY

DESCRIPTION

Also known as ARC1A_HUMAN, ARPC1A, SOP2L. Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Probable component of the Arp2/3 complex in which it may replace ARPC1B (Probable). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ARPC1A

Actin-related protein 2/3 complex subunit 1A

ARPC1A

Molecular Synopsis