FEATURES

FAMILY

DESCRIPTION

Also known as SC65_HUMAN, P3H4, LEPREL4, NOL55, SC65. Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. Interacts with PLOD1, P3H3 and PPIB. Identified in a complex with PLOD1 and P3H3.

Also known as SC65_HUMAN, P3H4, LEPREL4, NOL55, SC65. Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required f ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

P3H4

Endoplasmic reticulum protein SC65

Structural Ligandability

Domains Chains

0 chains assessed

1 chain not associated with a domain

P3H4

Structural Ligandability

Domains Chains

Distribution