FEATURES

FAMILY

DESCRIPTION

Also known as DNSL2_HUMAN, DNASE1L2, DHP1, DNAS1L2. Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DNASE1L2

Deoxyribonuclease-1-like 2

DNASE1L2

Molecular Synopsis