FEATURES

FAMILY

succinate/malate CoA ligase alpha subunit family

DESCRIPTION

Also known as SUCD_RICCN, sucD. Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. Heterotetramer of two alpha and two beta subunits.

EXTERNAL LINKS

uniprot
enzyme classification

sucD

Succinate--CoA ligase [ADP-forming] subunit alpha

sucD

Molecular Synopsis