FEATURES

FAMILY

DESCRIPTION

Also known as ACOX4_ARATH, ACX4, G6. Catalyzes the desaturation of short-chain acyl-CoAs to 2-trans-enoyl-CoAs (PubMed:10212254, PubMed:15743450). Active on butyryl-CoA (C4), hexanoyl-CoA (C6), and octanoyl-CoA (C8) (PubMed:10212254). Has no activity as acyl-CoA dehydrogenase or on crotonyl-CoA (an unsaturated C4:1 carbocyclic ester) or glutaryl-CoA (a dicarboxylic ester) (PubMed:10212254). Peroxisomal fatty acid beta-oxidation is essential for embryo development (PubMed:12682048). Acts as a suppressor of transcriptional silencing (PubMed:31064880). Required for nuclear histone acetylation and DNA demethylation at some endogenous genomic loci (PubMed:31064880). Homotetramer.

Also known as ACOX4_ARATH, ACX4, G6. Catalyzes the desaturation of short-chain acyl-CoAs to 2-trans-enoyl-CoAs (PubMed:10212254, PubMed:15743450). Active on butyryl-CoA (C4), hexanoyl-CoA (C6), a ...

EXTERNAL LINKS

ACX4

Mutations

Mutation(s) distribution

Mutations table