FEATURES

DESCRIPTION

Also known as PBIP1_HUMAN, PBXIP1, HPIP. Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling. Interacts with TEX11 (By similarity). Interacts with ESR1, PBX1, PBX2 and PBX3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PBXIP1

Pre-B-cell leukemia transcription factor-interacting protein 1

PBXIP1

Molecular Synopsis