FEATURES

FAMILY

DESCRIPTION

Also known as HAUS1_HUMAN, HAUS1, CCDC5, HEIC. Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. Associates with microtubules. The interaction with microtubules is strong during mitosis, while it is weak or absent during interphase. It is unclear whether this interaction is direct or indirect. Interacts with EML3 (phosphorylated at 'Thr-881') (PubMed:30723163).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HAUS1

HAUS augmin-like complex subunit 1

HAUS1

Molecular Synopsis