FEATURES

FAMILY

class-V pyridoxal-phosphate-dependent aminotransferase family

DESCRIPTION

Also known as MOCOS_HUMAN, MOCOS. Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MOCOS

Molybdenum cofactor sulfurase

MOCOS

Molecular Synopsis