FEATURES

FAMILY

DESCRIPTION

Also known as REEP6_HUMAN, REEP6, C19orf32, DP1L1. Required for correct function and survival of retinal photoreceptors (PubMed:27889058). Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity). Interacts with STX3 (By similarity). Interacts with clathrin (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

REEP6

Receptor expression-enhancing protein 6

REEP6

Molecular Synopsis