FEATURES

FAMILY

alpha-ketoglutarate dehydrogenase family

DESCRIPTION

Also known as DHTK1_HUMAN, DHTKD1, KIAA1630. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DHTKD1

Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial

DHTKD1

Molecular Synopsis