FEATURES

FAMILY

DESCRIPTION

Also known as FA20A_HUMAN, FAM20A. Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. Interacts with FAM20C; probably forming a heterotetramer of 2 subunits of FAM20A and 2 subunits of FAM20C.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FAM20A

Pseudokinase FAM20A

FAM20A

Molecular Synopsis