FEATURES

DESCRIPTION

Also known as RILP_HUMAN, RILP. Rab effector playing a role in late endocytic transport to degradative compartments (PubMed:11696325, PubMed:14668488, PubMed:27113757, PubMed:11179213, PubMed:12944476). Involved in the regulation of lysosomal morphology and distribution (PubMed:14668488, PubMed:27113757). Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments (PubMed:11179213, PubMed:11696325). Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes (PubMed:12944476). Homodimer (PubMed:15996637, PubMed:15933719). Interacts with RAB7A (PubMed:11179213, PubMed:14668488, PubMed:22431521). Interacts with RAB34 (PubMed:14668488, PubMed:12475955, PubMed:27113757). Identified in a complex with MREG and DCTN1; interacts directly with MREG (By similarity). Interacts with CLN3 (PubMed:22261744). Interacts with FLCN; the interaction is direct and promotes association between RILP and RAB34 (PubMed:27113757).

Also known as RILP_HUMAN, RILP. Rab effector playing a role in late endocytic transport to degradative compartments (PubMed:11696325, PubMed:14668488, PubMed:27113757, PubMed:11179213, PubMed:129 ...

EXTERNAL LINKS

RILP

Rab-interacting lysosomal protein

RILP

Molecular Synopsis