FEATURES

FAMILY

adenylyl cyclase class-4/guanylyl cyclase family

DESCRIPTION

Also known as ADCYA_HUMAN, ADCY10, SAC. Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation (PubMed:17591988).

Also known as ADCYA_HUMAN, ADCY10, SAC. Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function ...

EXTERNAL LINKS

ADCY10

Mutations

Mutation(s) distribution

Mutations table