FEATURES

FAMILY

DESCRIPTION

Also known as VP13A_HUMAN, VPS13A, CHAC, KIAA0986. Required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria (PubMed:30741634). Negatively regulates lipid droplet size and motility (PubMed:30741634). Required for efficient lysosomal protein degradation (PubMed:30709847). Interacts (via FFAT motif) with VAPA and VAPB (PubMed:30741634). Interacts with RAB7A (PubMed:30709847).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

VPS13A

Vacuolar protein sorting-associated protein 13A

VPS13A

Molecular Synopsis